The argument from efficient causality.

Music comes from a man playing a piano. If he stops, so does the music. If there is no uncaused being, there can be no thing.

Those who appeal to the physical laws of the universe to disprove the existence of God do not understand them. These laws demand that every effect have a cause outside of itself. Without an uncaused physical being outside the universe to set the chain of causality in motion, nothing could have happened within those laws. As I'm constantly reminding my wife, we can't win PowerBall without we buy a ticket. The odds of winning are 1:120 million or so if we buy a ticket, improbable to the point of absurdity, but still possible. They are infinitely against us winning if we don't.